Bone Marrow Aspiration & Trephine Biopsy Procedure
Contents
Indications
Preparing the patient
Contraindications
Instruments
Procedure
Transporting the specimen
Complications
Indication for Bone Marrow Aspiration
Diagnostic :
Idiopathic Thrombocytopenic Purpura
Aplastic Anemia
Leukemia
Megaloblastic Anemia
Infections e.g. Kala Azar
Storage disorders e.g. Gaucher’s disease
Pyrexia of unknown origin (PUO)
Myelofibrosis
Therapeutic :
Bone Marrow Transplantation
Contraindication for Bone Marrow Aspiration
Hemorrhagic disorders such as congenital coagulation factor deficiencies (eg, hemophilia), disseminated intravascular coagulation, and concomitant use of anticoagulants.
Skin infection or recent radiation therapy at the sampling site.
Bone disorders such as Osteomyelitis or Osteogenesis Imperfecta.
Complications of Bone Marrow Aspiration
Hemorrhage
Infection
Persistent pain at the marrow site
Retroperitoneal hematomas
Trauma to neighboring structures (e.g., lacerations of a branch of the gluteal artery) and soft tissues
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